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For information about this product's regions and endpoints, go to Regions and Endpoints in the Amazon Web Services General Reference.
If you just specify the general endpoint (ec2.amazonaws.com), the us-east-1 endpoint is used. If you want to use a different region, you need to specify the endpoint associated with it. For example, if you specify ec2.us-west-2.amazonaws.com as the endpoint, Amazon EC2 directs your request to the us-west-2 endpoint which is used for the US West (Oregon) region.
For more information about Regions, see Region and Availability Zone Concepts.